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The widespread resurgence of infectious diseases since the 1970s has stimulated many books about this ancient scourge. Following the lightning strike of HIV/AIDS in the early 1980s and its subsequent spreading wildfires, our sensitivity to threats from the realm of infectious disease has been reawakened. The many recent strikes, mostly from viral respiratory diseases, attest to the rising activity of ever-opportunistic microbes in an interconnected and rapidly changing modern world.
Rising world standards of living and dwindling population are two explanations for this resurgence. Lowered standards of medical care in Third World countries have led to the deaths of many who would have lived long lives, thereby exposing more people in the general population to illness. Another, more disturbing, explanation lies in the “ever-opportunistic” nature of microbes. Their evolutionary history with their hosts is only a glacial pace of change compared to the quick evolution of infectious organisms. The problem, as shown by the case of HIV, is that microbes that are “opportunistic” to some hosts can become so to others. Thus, while our immune system is still coping with viral infections, such as influenza or colds, opportunistic microbes are gaining new hosts.
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